Without doing a chemical analysis of my skin, I have no way of knowing whether these things really remove lead & other contaminants from my skin or not, so it's somewhat difficult to review this product when you're taking so much on blind faith. If nothing else, though, I at least feel better (psychologically) using a product claiming to be designed for lead removal. :-) Plus they're endorsed by the CDC.When you're working on five-to-ten guns at a time (think armorer duty or gunsmithing, or an annual spring cleaning of the gun safe), these wipes do a nice job of cleaning up your hands afterward. Everything comes off (grease, oil, solvent, and hopefully lead). The same is true after several hours of training at the range, which is especially important before eating lunch. For some reason, these don't seem to clean the little crevices between your fingernails & skin as well as, say, a plain Wet Wipe; but you can still get the job done with a little extra effort.While these wipes might do a great job of removing crud from your hands, I was disappointed that they didn't also remove the nasty solvent smells as well. Alas, the hands still smell like gun cleaner for hours after cleaning.I mentioned Wet Wipes earlier. My hands feel "different" after using these wipes than they do after using a Wet Wipe. I really can't describe the feeling... I want to say slimier, but maybe smoother is a better description... kind of like maybe the LeadOff wipes have some sort of hand lotion built into them, but it's a different feeling than that. Like maybe there's a chemical film left behind. It's no big deal and I don't know why I even mentioned it, but it is a unique characteristic of this product. As soon as you're able to wash with regular soap & water everything is back to normal.The product description says these wipes also remove dirt, grime, and most common germs. If I'm interpreting that correctly, then not only do these remove lead from the skin, but you also get the added benefits of a regular Wet Wipe (cleaning) and Purell hand sanitizer (removing germs). Not bad.These wipes are pricey (IMO), but I think they're worth it. I don't say that about many things. These are now a staple of my gun cleaning supplies. I wish they would come packaged individually like a Wet Wipe, though. It would certainly be a lot easier to pack a few individual wipes into a range bag or armorers kit than having to deal with a huge container, not to mention worrying about whether I have to keep the container in an upright position to avoid leaks/spills or not.UPDATE: 8/1/161. In the original review above, I said that these were pricey. At the time of that review this item was going for $11.99/canister, so the price has actually come down a couple bucks now. I still think they're a little expensive (compare to a 40-count cannister of Wet Wipes @ $5.74), but the new lower price is more reasonable.2. I also said that I wished these wipes came individually wrapped. My wish was granted (hooray!). However, you're going to pay over 3x more (per wipe) for the convenience. A 25-pack of individually wrapped LeadOff Wipes currently goes for $16.99. Clearly this item (i.e. the canister) is your best value for the wipes.